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Cedars Sinai

Skin and Nail Biopsy

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Skin and Nail Biopsy

Accurate Diagnosis Through Skin & Nail Biopsy

Accurate Diagnosis Starts with Precision Testing

When dealing with unexplained skin lesions, nail discoloration, or chronic rashes, a proper diagnosis is essential for effective treatment. At SoCal Foot and Ankle Doctors, we offer in-office skin and nail biopsy procedures to accurately evaluate dermatological conditions affecting the feet and toenails.

With locations in Santa Monica and the Cedars-Sinai Medical Towers, our board-certified podiatrists use minimally invasive biopsy techniques to detect infection, cancerous lesions, fungal disorders, and autoimmune skin conditions. Most procedures are quick, painless, and performed under local anesthesia.

Why Is a Biopsy Needed?

A biopsy is a safe and highly reliable procedure used to diagnose:

  • Suspicious moles or lesions
  • Non-healing wounds or ulcers
  • Nail abnormalities (thickening, streaks, discoloration)
  • Chronic rashes or scaling
  • Possible skin cancer or precancerous lesions
  • Diabetic skin changes or infections
  • Unusual pigmentation or bleeding

Early diagnosis allows us to start treatment immediately and potentially prevent serious complications.

Common Conditions That Require Biopsy

Fungal Nail Infections – Determine if discoloration or nail thickening is due to fungus, psoriasis, or trauma
Plantar Warts – Differentiate from calluses or precancerous lesions
Squamous Cell Carcinoma or Melanoma – Rule out malignancy in new or changing skin growths
Lichen Planus / Psoriasis – Chronic skin or nail diseases often require biopsy to confirm
Diabetic Foot Ulcers – Identify infections or abnormal tissue changes
Chronic Athlete’s Foot – For persistent scaling, irritation, or breakdown

Types of Biopsies We Perform

???? Punch Biopsy – A small circular tool removes a full-thickness skin sample
???? Shave Biopsy – The top layer of skin is shaved off for superficial lesions
???? Nail Matrix Biopsy – Used to evaluate pigmentation, nail plate irregularity, or suspected melanoma
???? Wound Biopsy – For chronic, non-healing diabetic or venous ulcers
???? Curettage – Scraping technique to evaluate wart-like or crusted lesions

Each specimen is sent to a dermatopathology lab for analysis with results typically returned in 7–10 days.

What to Expect During and After the Procedure

  • Local anesthetic ensures comfort
  • Most biopsies take less than 10 minutes
  • A small dressing is applied, and post-care instructions are provided
  • Mild soreness or tenderness may occur for 24–48 hours
  • Return to normal activity is often immediate unless otherwise advised
  • Cosmetic scarring is minimal with proper care

When Should I See a Podiatrist?

If you notice:

  • A mole or lesion changing in color, shape, or size
  • Persistent nail streaks or darkened areas under the nail
  • A sore or wound that won’t heal
  • Chronic itching, burning, or scaling of the foot
  • Thickened, crumbling toenails resistant to treatment

Don’t wait—early biopsy can save lives and improve treatment outcomes.

 went to Dr. Hassid yesterday for the first time. The office is so welcoming and nice and I love, love, love Dr. Hassid. He is very thorough and really explains everything that he is going to do. He is very warm and caring and really listened to me and made excellent suggestions. He took x-rays right off the bat and established what was really going on with my foot. I am going to try his suggestions at home and return for a check in two months. I would highly recommend this office!!!

Karen Lepp

I was referred to Dr. Hassid by an urgent care, due to a toenail infection. I am so glad that I went to Dr. Hassid for my treatment! Him and his whole office staff were super professional. Dr. Hassid listened to all of my questions and patiently answered them so I knew how to heal quickly. I had to reach out via email a couple of times with some questions, and he responded super quickly which made me feel like he truly cared about how I was feeling. If I ever have any foot problems in the future, he’s the man I will be going to. Thanks for everything!

Carly O.

Dr. Hassid is presently treating my plantar fasciitis . He gave me several options to choose on my treatment and fully explain all the details. I choose Shockwave therapy even though my insurance doesn’t cover. Dr. Hassid & his staff were so friendly & accommodating. I hope all doctors are as compassionate as Dr Hassid. He listens and answers all your questions the bests he could. You can’t go wrong going to him. Dr Hassid, may you continue to blessed in everything that you do….Thank you

Fely Tanagon

Our Docters

Our Board Certified Podiatrists

Socal Foot and Ankle doctors are committed to delivering the most exceptional treatments.

Board Certified Foot & Ankle Specialist

Board Certified Foot & Ankle Specialist

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